The story is set in a near-future Earth, in the aftermath of a major disaster that shifts the planet's polar axis 90 degrees, situating the poles along the equatorial line and killing everyone on Earth. A moon-based colony avoids the disaster, and begins recolonizing the depopulated Earth by establishing seven cities in strategic locations. However, to ensure the loyalty of the Earth colony, the moon establishes an orbital defense system that destroys anything that flies 500 meters in the air. When an unknown virus kills everyone on the moon, humanity becomes trapped on Earth, where the political intrigues of the seven cities continue to play out.

The story begins with an attack on humanity by giant indestructible monsters named "Enemies". The Enemies drive humanity to the brink of extinction... but the one to save the world from the depths of hell is a lone boy!
The SF novel series by Kafka Asagiri (Bungou Stray Dogs) jumps into the manga scene with art by Anri Sakano (Sayonara Peter Pan)!
Is he God or is he the Devil...will the amnesiac protagonist Kyle Kamishiro bring a future filled with hope, or...!?

There exists a secret organization that has members traveling across time to save people from their wrongful deaths. Namihira Bon accidentally learn about the Time Patrol, and is recruited as an apprentice member. Together with Rim, the patrol in charge of mentoring him , Bon goes to various historical periods to rescue innocent people, trying not to alter history in the process.

On a day just like any other, a giant spaceship suddenly appeared and invaded Earth, obliterating entire cities in the blink of an eye. In the midst of the attacks, Kanna Fujimiya, amateur content creator, rose to fame overnight with her video coverage of the invasion. With her newfound popularity and charms, Kanna continues to cover the war from the front lines, but...!?

This amateur content creator reveals the truth behind the interstellar war in this science fiction thriller!

In the near future where Android (A.I) becomes common among humans, a virus outbreak suddenly occurred, turning over 70% humanity into zombie-like "Creatures." The A.I soon break away from their infected owners since they're not programmed to recognize "Creatures" as humans, but one of them, the housekeeper Hasty, acted otherwise when her infected young master, Neville's final words struck something in her. Sticking with him after all other humans have been infected in the area they're living in, Hasty vows to do whatever it takes to cure master Neville, even if she has to fight against the whole world who's now looking to exterminate all Creatures to cut off the infection source completely.

Seventeen years ago, the Crossbone Gundam was lost in the fight against the remnants of the Jupiter Empire in the “Thunderbolt of Zeus” operation. Now, the mysterious mobile suit walks again on the streets of Side 3, called back from beyond the grave thanks to a young high schooler named Font Baud and his discovery of the Zanscare Empire’s trump card. Who is the mysterious blind pilot of this “Silver Ghost”?

From MangaHelpers:
Nogawa Izumi is a good student, and a class representative, but she has an increasingly high libido. It's gotten to the point that she'll claim to feel bad during class, so she can run to the nurse's office and masturbate. When she learns that the Earth is being invaded by aliens that look like people dressed up as animals, it turns out her high sex drive may be able to help protect the Earth. The first time Izumi is attacked by the aliens, she is rescued by Usayama, a bunny alien whose race was their previous victim. Usayama gives her a swimsuit that will allow her to fight the aliens, but which also sends her constant arousal through the roof. The scientific organization that Usayama is affiliated with think that Izumi, with her high erotic level, may be the person they've been looking for to fight the aliens. Will Izumi be able to save the Earth?

In a world where heroes fight against evil from space sometimes they get hurt... and in comes a man with special powers... a massage that heals.

A gate to another dimension has burst open, and from it emerge gigantic, invincible creatures that threaten all of humanity. Earth's only defense is a mysterious group of warriors who have co-opted the alien technology in order to fight back!

Metalia, a world where mechanical creatures called the gears stroll. It was the so-called "machine hunters (collectors)" who hunted those who ruled the earth with mighty power. A boy now descends in Melzam, the largest city in Metaria. His name is Nill. He, with the right arm of the machine, had a secret. This is a story that looks for your fate.

KUZUNO Sekai was transported to a medieval fantasy game-like world (isekai). He was given a game controller with the ability to stop time and a 3 days countdown timer. Now he has to figure out the mechanics of this game world and clear it in time.

Five hundred years ago, Rudolf von Goldenbaum united the disparate governments of humankind and established a mighty human empire, a tribute to his own greatness that stretched across the galaxy. Demanding loyalty and discipline, Rudolf created an order designed to long outlast his own rule; but all human works fade in time. Today, the decaying empire faces the threat of the Free Planets Alliance, and military leaders on both sides jockey for power in the face of a seemingly inevitable conflict. On the side of the empire, the young general Reinhard von Lohengramm sees war as opportunity, and the empire as soft clay ready for his own sculpting. On the side of the alliance, would-be historian Yang Wen-li would like nothing better than to live out his days in peace - but times of war have little use for men who waste their days studying the mistakes of the past. Circumstances will make heroes and villains of both these men, as they write new history one blood-splattered page at a time.

A world where machine civilization has perished and immortal monsters called "Monotsuki" are rampant. Isana, a girl born in a remote village, meets a mechanical person who lost her memories and looks exactly like her sister, who should have disappeared in the ruins she wandered into. Convinced that "My sister is alive," Isana gives the mechanical person the name "Hime" (princess) and together they set out on a journey to find her sister.

A space series about a protagonist who continually fights against all the aliens who are trying to take his life.

"Yukio... I'm going to make a friend." A shy boy named Tetsuo. The only thing he had was a giant robot named Yukio. They became "saviors" in the fight against the galactic monsters coming from outer space. After the final battle, Tetsuo returns to Earth for the first time in ten years and witnesses an astonishing world. It's a frozen Earth (named Snowball Earth), where the entire land is covered in snow and ice, being turned into a deadly world! What happened to the human race? And will Tetsuo be able to fulfill the promise he made to Yukio?

From Viz:
In the 21st century, just when the human race needs new heroes, the Lucifer Hawks enter Earth's dimension. The members of the A.M.P., six young women with incredible powers, are set to defend the human race against these monstrous entities from another world.

Liam Sera Banfield is a reincarnator.

He was reincarnated into a fantasy universe of swords and magic, but at a time that civilization was already making advancements into outer space. The setting takes place in an intergalactic empire, a space opera-like universe where humanoid weapons and spaceships do battle. Liam, who had incarnated into an aristocratic family in a monarchic society, has the ambition to one day become an evil lord. In his previous life, Liam had unfortunately lost everything and died in despair.

"It’s foolish to live for others. I will live for myself."

Holding those feelings in his chest, he starts towards his second life, but is instead worshipped as a virtuous ruler from his difference in values. Will Liam be able to safely become an evil lord?

Very few adolescent boys and girls have an onset of special abilities. Yuu Otosaka uses his ability unbeknownst to others in order to lead a satisfying school life. And then, a girl named Nao Tomori suddenly appears before him. Their encounter reveals the destiny for wielders of special abilities.

It's the 21st century, and the number of ESPers continues to increase. They are active in the military, diplomacy, politics, and in other places. They hold the key for global competition. A country that controls ESP can control the world! However individuals who posses higher than Level 4 are less than 3% of the population. There are only three Level 7 people who have government contracts. These three are Kaoru, Aoi, and Shiho, ten-year old girls, who work for B.A.B.E.L. With the guidance of Kouichi, a twenty-year old genius, they catch criminals and evil ESPers.

Kaede Mizumori, a high school student who can see through people's lies, lives a dry life so as not to make waves. Until he meets the mysterious schoolgirl Rin Homura --- a thin sci-fi alien drama.