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TruePurpleMK
1500 points
Level 73
3916 Comment(s)
2645 Upvote(s)
I did mention the witness in the post you replied to... Also the blackmail material and MC to kick ass....
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I think the hand print is more symbolic. I doubt they are doing fingerprint analyses in that low tech environment,. There was witnesses and the master has acquiesced Unless maybe some magic energy is left behind, though I doubt it.

Not only are there witnesses, there is MC to kick his ass, and blackmail material if they try to weasel out of paying
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TruePurpleMK R Tuin - 1742848023
if you say so
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TruePurpleMK Phobia - 1742776088
"You don't go and pick up a coin from a pot of boiling water, especially if there's a similar coin in a pot of lukewarm water."

Not sure what that has to do with getting buck naked to not be seen by a creature sensing heat, but if you understood insulation then you would know you'd be less visible to something that senses heat if hiding under insulation AKA warm clothing. Insulation traps heat in, which means it doesn't leak out as much for heat sensing beasts to see. Also if your more exposed your body automatically works harder to heat you, making you even more visible to to the thermal vision monster.
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TruePurpleMK Phobia - 1742773490
OK? You have some kind of point?
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TruePurpleMK Nagaoal12 - 1742757746
I don't recall offhand, does lots of comparison stuff like is expensive X similar to cheaper version of it, difference between vanilla beans verses natural extracts verses artificial flavoring, there is one about rice and different results based on water ratio and other things, brown eggs verses white etc. Does blind taste tests to compare things. If I see that YT recommended again and remember, I'll post the name here.
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For this to be a issue as far as I can tell you need two things, tell me if you think I am wrong.

1, The donor's white blood cells must see the hosts cells as a threat.
2. The host's immune must not see the donors white blood cells as a threat or must be unable to respond to foreign white blood cells. The first part "not seeing the donors white blood cells as a threat" is higher with familial blood but irrelevant without a functioning immune system.

Thus for someone without a immune system, ALL foreign white blood cells can become unchecked threats to the host. "risk of TA-GvH is worse in immunocompromised recipients" Yes, but not because of familial blood but because of lack of immune system. Lack of immune system increases the risk of everything but familial blood. Since no immune system means only first point matters, "donors white blood cell's must see host as threats" then familial blood reduces risk since closer matches mean less risk of donor white blood cells attacking.
"most effective ways to get rid of leukocytes we have today are only so effective before they also get rid of too many erythrocytes (centrifuge+buffy-coat, freezing"

AKA Leukoreduction AKA remove the white blood cells from the donor blood. MC should do that and it will reduce the risk. How much, hard to say- Suffice to say my previous points remain. Without a immune system the issue becomes any donor bloods Leukocytes, not just familial.

https://www.sciencedirect.com/science/article/abs/pii/S1473050222000647

All that is left once you remove donor white blood cells is better match with close family members. Donated blood can have delayed rejection issues well down the road that you can not test for, familial blood reduces this risk.
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Yeah it's possible. But lack of immune system or weaker immune system makes it more irrelevant. Since the issue is the hosts immune system not seeing the donor white blood cells as a threat. But the donor white blood cells seeing the hosts cells as a threat. A extremely unlikely but possible scenario. With less immune system response in the first place this becomes less relevant. In fact close relative compatibility just makes the donor white blood cells less likely to attack the host in the first place.

MC needs to separate out the donated blood removing white blood cells using some kind of centrifuge machine (maybe using a bicycle powered setup since no motors, or using magic powers to spin it). This should be done anyways to avoid all sorts of potential problems, especially with a patient with a weakened immune system. That will help with all risk to TAGVH family or not

The bigger issue is that MC lacks means to properly test blood types and is limited in blood testing compatibility. Family blood is most likely to be compatible and would best to be used in this scenario. Sibling would be best as that is the likely closest match. Though MC's weird properties probably mean sister would be the best donor candidate, assuming full siblings.


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TruePurpleMK - 1742682249
https://i.postimg.cc/GmyCXQf6/i.png

OK I did some research https://www.quora.com/Why-cant-a-patient-receive-blood-from-a-family-member

Basically the white blood cells of the donor blood may see ALL of the hosts cells as "invaders" and attack (extremely small chance) But in a relatively healthy person who isn't immuno-compromised d the persons own white blood cells will fight it out with the donors white blood cells, under normal conditions the hosts will easily win the battle vastly outnumbering the donor white blood cells.

But if the donor is a extremely small chance that the donor and host white blood cells do not see each other as threats/invaders but the donor white blood cells may still see the hosts other cells and tissue as foreign and attack, without the hosts immune system protecting. This can be tested for. I assume as simple as mixing the blood together under a microscope strong enough to see this and seeing how the cells interact.

But, if the host is immuno-compromised then this "donor white blood cells left unchecked attacking host" is much more likely to happen and it will be irrelevant if it is a relative since no immune system. Maybe it would still matter a bit if he's just got a weaker immune system instead of a completely disabled one. There is method to prevent this from happening other than checking ahead of time for reaction, which is to treat the blood so to kill the white blood cells of the donor or separate out the components of the blood so no white blood cells are transfused. Otherwise just testing for this reaction. Considering the risk, the effort should be made to do this, and that would make it irrelevant if it were family donor or not.

In fact, higher compatibility "HLA" means less likely for there to be a issue if the blood has not been stripped of it's white blood cells (vast majority of modern blood donations are treated to remove the white blood cells) Thus it would be better to be a family member.

According to chatgpt the odds would be 1 in 500,000 to 1 in 1 million if not family members to 1 in 1 million to 1 in 5 million for a properly matched family blood transfusion. Of course the odds are zero if the blood was treated to remove the white blood cells.

So the story did get it wrong, just in a way I did not expect. The description of the concern is wrong and it's only a additional risk in someone with a working immune system and irrelevant if you kill or remove donor white blood cells which should be done anyway.

Also it seems there is difficulty in testing blood type without modern lab equipment and family member blood is much more likely to be compatible and would be your best bet
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TruePurpleMK - 1742581300
That grade ranking business is so bad.
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TruePurpleMK - 1742581032
Frustrating that they are giving no effort to prevent this power transfer business Like maybe disable one of them without technically killing them? Where is MC?!?
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TruePurpleMK - 1742564189
https://i.postimg.cc/BZpG9HcR/i.png

I was thrown by the use of the word "resurrect" but maybe it means "I can bring them back as mindless undead but not back to life"?
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TruePurpleMK - 1742509114
Wow, super twisted and evil.
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TruePurpleMK - 1742501655
It could all be a lie anyway.
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TruePurpleMK - 1742498753
Let MC have a day off FFS
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TruePurpleMK - 1742497236
Geez to beat em up for a bouquet....
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TruePurpleMK - 1742494442
So exploitative, but I did know that about japanese comic industry
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TruePurpleMK - 1742493847
All that effort with the nipples but those damn lousy manga faces....

Also so many tired lewd accidents in one chapter.
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TruePurpleMK - 1742485830
https://i.postimg.cc/QMVh3R61/i.png

What's this nonhuman (pointy ears and fangs) guys deal...
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