Decades ago, the tiny town of Hanaizawa was cut off from the rest of the world by an invisible wall, a wall that nothing living can pass through. The younger residents have grown up only knowing the outside world through what they see and hear in the media. These are the stories of their everyday lives, the good and the bad, as they live out their days in a tiny town that no one can enter and no one can leave -- a town which, by its isolated nature, is destined to fade away.

The daily lives of a 15-year-old orphan and the 35-year-old lady novelist she ends up living with, and what happens when two polar opposite worlds try to -awkwardly- interact.

The short stories of Tomoko Yamashita.
First girl: There was a girl in the middle of the gruesome incidents. ‘I thought that I was invincible.’
Second girl: A recollection of ‘a girl’ who didn’t love an excellent boy, ‘me’.
Third girl: The future where you are cursed when you are born. The only girl who wasn’t cursed is nervous about her undecided future. ‘She is pitiful for not being cursed!’.

Teshima Hibari is a 14 year old girl with a body that is more sensual than most girls her age. Her story includes the opinions and reactions of all of the people around her, as well as the actions of her own life. The chapters explore the thoughts and feelings of classmates and adults, men and women. The males often have romantic or sexual feelings for Hibari, while the women sometimes have feelings of inferiority or jealousy. Whether positive or negative, it seems everyone has a reaction to Hibari. 

28-year-old Kiwako meets a man who smoking on the balcony one day. Her next door neighbour, Nuihara, a lazy, 52-year-old college professor.
As Kiwako is considering abandoning her career as a ballet dancer, he gives her some sincere advice. Until now, Kiwako had given up on love, but his words have stirred up a passion within her.

A collection of oneshots:

1) Touch Me Again
Seven years ago, Touda and Oshikiri crossed the friendship line once. Right after that incident however, they chose to pretend nothing had happened just so they could go on being best friends. But life is never so simple and seven years later, they begin to see the strains in their relationship show.

2) Iki wo Tomete,

3) Heavy Sugar no Iyagarase

4) Candied Lemon Peel

5) nuotatore nel cantero!

6) Stars Spica Spectre
Kiji is paid a visit by the ghost of his dead friend, Osaka. Although Kiji sees Osaka, it is only an afterimage of his friend, as Osaka's spirit is actually in Spica, a star that is 260 light years away from Earth. As a result, everything Osaka says goes through a time lapse and Kiji only hears him after the afterimage disappears. This is a sad, poignant story about two men who never found it in themselves to confess to each other until it was too late.

7) Ushi Meshi

8) touch IT again, again, again & again

9) I cannot breathe without U

10) lemon crush, bitter & sour

11) Spica no Su wa Sushouyu no Su

From Storm in Heaven:

1-3) Illumination

Twenty-nine-year-old Mikita Ryuuji has been hiding his love for his friend Koya for so long that he can't take it anymore. At his wit's end, he spends one night with Sudo, a man he met at a bar. It was supposed to be a one-night stand, an event he'd forget about the next day with someone he'd never see again. But when Sudo does show up again, this time determined to stay for good, Mikita's life starts to fall apart...

4) Love, or Something

5) Roses, Thorns and a Shattering Clang

6) About Him

7) God's name is Night

8) - extra stories

From MAL
This fanbook contains short manga as well as illustrations, an interview, and features about Natsume Isaku's working habits. There are a series short manga starring the characters from all of Natsume Isaku's mangas interacting with each other. Other mangaka also contribute short manga featuring Natsume Isaku's characters. 50 new pages have been drawn especially for this fanbook.

[From Nakama]

Since there is no back cover blurb here are the contents:

Natsume Isaku Special Illustrations
Let's go to the super bath-house! … 3
Amber Paradox - Masaya and Satoshi … 11
Amber Paradox - Tale of the Night … 18
Tight rope - A tale, half asleep and half awake … 27
Doushiyoumo Nai Keredo - Night of sake … 36
Doushiyoumo Nai Keredo - Let's go to my parents' house! … 41

Popularity poll results — publication … 53
Question for Natsume Isaku-sensei! … 64
Color Illustration Selection … 65

Guest Comics
SHIMIZU Yuki Sugar Code Yakuza Man … 97
YAMASHITA Tomoko Amber Paradox Onoe is definitely set to smash an important setting* … 101
AMAGAKURE Gido Doushiyoumo nai keredoYou're cute whatever you do … 105
AMAGAKURE Gido Ikasama Memory A promising future … 111
YAMADA Nichoume Heart no Kakurega Arm pillow … 113
YAMADA Nichoume Heart no Kakurega Rolling arm pillow … 115
YAMADA Nichoume Doushiyoumo nai keredo
A satisfactory arm pillow … 116
MONCHI Kaori Tight rope Sleeping on someone's lap … 117
Koshino Amber Paradox Paparazzi hotel … 122
— Guest Profile & Message … 124

Uncompiled Tankoubon Comic and Illustration — Re-compilation
Doushiyoumo nai keredo Flower Friday ④ … 126
Doushiyoumo nai keredo Before the morning sparrow disappears … 141
Doushiyoumo nai keredo Something very unexpected** … 149
Tight rope Ryuunosuke's Delusional Diary Part II … 153
Sugar Code Limited AGF book (2010) Special Illustration … 164
— Comic papers … 140, 165
— Illustrations and cuts … 172

Natsume Isaku Long Interview … 174
A look at my working space!! … 183
Super storyboard exhibit!! … 184
“Tightrope” OVA Creation plan exhibit!! … 185
Character rough plans exhibit!! … 186
Background illustrations exhibit!! … 188
“Heart's refuge” Tenement house room assignment and arrangement exhibit!! … 189
Natsume Isaku publication list … 190

HER is a series of character portraits, loosely strung together by everyday circumstances. The story begins with a woman who wants to be loveable - and loved - and who has a fixation on shoes. Her hairdresser's fear of the future is the subject of the second chapter. A schoolgirl whose hair she cuts sees her older female neighbor kissing her female lover goodbye. In the past, the neighbor had a difficult relationship with her mother. The neighbor's lover was rejected by her first love. The couple sitting next to them at the cafe have their own issues.

A collection of short stories:

-Stroboscope
Kazu, the owner of a run-down coffee shop, becomes the inadvertent host to Renji, a young man who perceives Kazu's hunger for the touch of another person. The pain of this realization only increases the torment of Kazu, who has long ago given up on his longing for love. [Warning: Talk of a suicide attempt.] - Must be Endless

-Chain Gang
Always together, one man drinks at another man's home when he can't catch the last train home, but what is this feeling of deprived freedom? - Yaoi is Life

-Good Morning, Bad Day

-Devil's Thoroughbred
Kinaga-s act of kindness and friendship is repaid in the most unexpected way. Yamashita Tomoko's pre-debut work! - Echochi Scans

A pure but unusual love story of a girl who ventures into femdom.

A collection of short stories. 1) Love Dancing Beneath My Eyelids College student Numakami has known for a long time that his classmate Mahara is in love with him. But Mahara is pure, innocent - and still a virgin. For some inexplicable reason, this makes Numakami feel annoyed at being the object of his affections. 2) She's Missing Yanagi is in love with Kobayashi, who can't seem to stop talking about Adachi - a girl in their class. What will become of these three teenagers and their complex relationship? 3) Minun Musiikki A quiet pianist and an obnoxious, outspoken cellist often find themselves alone in the music room together... 4) Yes It's Me The story revolves around Toma, who is head-over-heels in love... with himself! However, so is everyone else around him; and he knows that his business partner and old friend, Enoki, is no exception. Toma doesn't blame him. After all, he is only the most brilliant, beautiful, and all-around perfect person to ever walk the face of the Earth! Who wouldn't fall for him? Weirdly enough, Enoki is convinced that Toma returns his feelings. But they should both know by now that there's no one he loves more than himself... right? 5) Yes It's You 6) Loathe! 7) Dreams Unfold at Night 8) Yes That's It

Thanks to her parents' incompetence, Taeko is sent to live with an acquaintance of her father. But when she rings the bell of her new home, she's greeted at the door by her new roommate, a completely and utterly shameless nudist named Masuda. Why exactly is he presenting himself in the buff to an innocent high-school girl...? Of course, their shocking first meeting sends Taeko's 17-year-strong values tumbling to the ground! "Is he for real?!" "Am I going nuts?!" It's too late for tears, so Don't Cry, Girl - a hilarious teen comedy ♪!

Source: Jmanga

It also includes a second story called 3322. (Unscanlated)

Nominated for the 4th Manga Taisho in 2011.

1) The Turquoise Morning
A well known photographer named Jed Knox acquires a one-sided love from his time in a foreign country. Because the target of his crush, Sahab, said he would never love another since his wife died, Jed would never tell of his feelings. Oh but how Jed wished Sahab would love him even a little bit and that he could have Sahab's soul in his hands. Although ifrits (genies, etc) are magical wish givers in story, what could happen if they were real?

2) It's Time for Goodbye
It is the morning after and the student finally notices that the lover's room is exceptionally sparse.

3) LOVE-ING
A guy tells his friend that he's gay and in love with him, but his friend is surprised and leaves.

4) Playboy!
He has had it. His lover won't make love to him and refuses to stop seeing other women.

5) The Eyes of the Rose are Bombs
The prince-like Hansumi has an effect on everyone around him, except Mitsuda.

6) Aah Boyfriend
Suzuki can't stop fantasizing about his friend.

7) Garden of Despair
Isuka is still trying to come to terms with his feelings for his friend.

8) The Eyes of the Rose are Blind
Continuation of chapter 5.

9) Garden of Desire
Continuation of chapter 7.

10) Bad Boy
Continuation of chapter 4.

11) Go Go Boyfriend
Continuation of chapter 6.

12) Postscript

Mine the translator and Anjo the bus driver are friends. Mine is awkward and hard working, while Anjo is friendly and has a girlfriend. They're very different from each other, but they quickly became friends and feels a strange sense of distance between them.

From The Moon in a Box:

Before Minari knew he was gay, he convinced himself he was incapable of falling in love. Having spent the last five years settling for just sex with a friend from high school, he surprises himself by falling in love with and impetuously confessing to an acquaintance, Shinkawa. But will Minari's fragile ego be able to withstand the fear and uncertainty of a real love relationship?

A collection of short stories:

-Stroboscope
Kazu, the owner of a run-down coffee shop, becomes the inadvertent host to Renji, a young man who perceives Kazu's hunger for the touch of another person. The pain of this realization only increases the torment of Kazu, who has long ago given up on his longing for love. [Warning: Talk of a suicide attempt.] - Must be Endless

-Chain Gang
Always together, one man drinks at another man's home when he can't catch the last train home, but what is this feeling of deprived freedom? - Yaoi is Life

-Good Morning, Bad Day

-Devil's Thoroughbred
Kinaga-s act of kindness and friendship is repaid in the most unexpected way. Yamashita Tomoko's pre-debut work! - Echochi Scans

1. La Campanella - Two co-workers and their uncertain relationship.

2. Love's Magic Word is... - A gaming enthusiast tries to confess to his long-term friend.

3. Saturday, Boy, Phenomenon - A reunion between two classmates: the guy who was outed in high school, and the "best friend" who outed him.

4. The Sorcerer's Apprentice - "All the neighbourhood ladies tell me to stay away from that house where the crazy gay guy lives. But I'm a girl, so I guess it'll be safe for me to pay him a visit now and then."

5. Cu, Clau, Come - A gay guy cooks meals for his straight friend several times a week.

6. Once Upon a Time in Tokyo - Tokyo: where country people go to leave behind rural life, with all its close-knit relationships and painful first loves...

7. Je t'aime, cafè noir - In a small coffee shop somewhere in the city, five customers coincidentally come together. Two of the employees there also get involved, paving the way for four mini-dramas to ensue.

Each of the high-school students in the small dance club are there for a different reason. Natsu joined due to her love of hip-hop dance, and Haba Takahiro's presence is all thanks to some relentless bullies. Whatever brought them all to the club, they're now learning about the different styles of social dance from the skillful vice president Kazumi and the hesitant president Hajime. As they learn the joys of dancing, they will also grow closer to each other...