Three sisters, Isuzu, Aoba, and Haruna, inherit an electronics store in Akihabara from their dead father, but their business is not doing well. Creditors have threatened to seize their shop if they cannot pay their bills. They find a heart-broken otaku named Takezou Muto on the doorstep of their shop, and he is able to save the day and the shop with his quick thinking. He is hired on permanently, and Haruna, the motherly sister, asks him to transform their store into a money-making enterprise. Takezou dreams of it becoming an otaku paradise, much to the delight of Isuzu and much to the consternation of Aoba.

Morita, a hopeless otaku, falls in love with his popular classmate, Sakura. As his otaku approach to woo Sakura collides with reality, things heat up. Will he be able to become the man that Sakura desires? A sexy and funny story about the reality of love. (Adapted From) Erotikku ni Oborero! (Sequel) Chou Maniac ni Aishite

From ShoujoMagic:

Homare is a lovely first year high school student who has been sold off to the Ichinokura family as payment for her parents' debt. Although there are only guys in the Ichinokura family, they are all clean and kind, and Homare works hard as a pretty maid, including washing their underwear and their backs!

The ever lasting war between good and evil rages on..or at least that's what he was lead to believe!A young boy becomes the prize for which the legions of heaven clash with the hordes of hell.Being deceived by God and prosecuted by Satan,Malei Damakotto bears the burden of power that could be a grand asset or a terrible scourge for either one!Malei will stand against a fate predetermined by the self proclaimed lords of this world and bend both the will of light and malice of darkness under his fist!Wings shall break and claws shall shatter as he enters the battle of battles on his own right!

Mitsuru Masamune, a mild mannered high-schooler who hasn't had much of a presence since his birth one day had a roommate move in.
A silver-haired, blue eyed exchange student all the way from Germany, Leo.
They had a dignified appearance and had a cool way with their words with no room for timidity.
He used to think that Leo was a being far off from someone like him till he got to know about a secret of his after which their relation got a bit more special...?!

Lucas has a hard life. In his mid-thirties, a mixture of failures has left him old and crippled, playing pack mule to a couple of young adventures.

Then one day, he pulls a magic sword from a stone that tells him he has been chosen to become a hero. Given a youthful form, Lucas must use the power of the sword to vanquish evil and attain a massive harem.

Before you ask, it’s not isekai because he’s been in this world from day one. It is wish fulfillment, though, so in the end it’s basically the same thing.

From Shoujo Sense:

The packed morning train isn't a good place to be if you're small; a fact that high schooler An knows all too well. So when a boy rescues her from the crowd one morning, she should be grateful... right? The only problem is, he treats her like a little kid! Who is her rescuer, and what will happen when she meets him again...?

In the land of Glengard, the realm's 666th Demon King, Fienalia Glengard Flamveil...is bored. With no challenges to excite her and all of humanity long since subjugated, she's off to find a new worldany world!to conquer...and it just so happens that Earth is next on the hit list! But when "Ena-sama" meets Kento Sugitani, an aspiring manga artist, it seems she might have found a new hobby more interesting than world domination. What is a demon lord to do but enroll in a manga school herself?!

(Source: Yen Press)

Abe Maria, an ordinary high-school boy and Nanami Tokuko's childhood friend, is the world's last pureblood vampire!! For 10 years, Tokuko has been encouraging him to become a part of human society, and since then, Maria has come to love humans. As such, Tokuko happily watches over Maria. This couple's story is the world's most gentle vampire comedy.

*Includes an extra story called Manshinsoui no Futari (The Wounds that Cover Us) in vol. 1 detailing a high-school romance between a boy who is suffering mentally and an extremely clumsy girl.

A collection of several absolutely intense and violent stories. They are gorey and crazy. The first is about a woman who has mantis-like arms and uses them to sever heads, and then in turn uses those heads for her own special purposes... Read to find out. The same main character is used throughout. If you love murderous koala bears, read!

The protagonist is a player of a VRMMOFPS game who ends up falling off the map while playing in PvE mode, and ends up being transported to a fantasy world with his FPS system.

Ryuu always protect her friend Kikuyo from boys because she thinks that they are beasts. What will she do when Kikuyo finds a good boy? Why does she protect her so much?

From LINE Webtoon: At the first day of his school, Gamin saw something that he shouldn't have seen and from that day, his previously witch-less life became double double toiled and troubled. Original Webtoon / English Version by Naver

From Operation Boredom:
It is currently the Taiheimeji Era. It is a reign ruled by the Tokugawa shogunate. Inside this shogunate, there is a group of warriors that support the government. They are the Manyuu Clan. In this current era, breasts mean everything. If you have breasts, you are guaranteed wealth and popularity. If you lack them, you are rarely considered "human". Members of the Manyuu Clan help raise the future big breasts. Written on a secret scroll possessed by the clan, there is said to be various techniques on how to grow big and beautiful breasts. Chifusa is to be successor of the clan. However, she takes the secret scroll and runs away with it, hoping to fight against the cruel world that the Manyuu Clan has created.

An over-the-top, vulgar, grotesque and yet hilarious gag manga about a cute little girl in hell.

The story is set in a “land where two worlds intersect,” and it centers on “a strange romance between a boy and girl who meet by fate.”

The great demon Mao Dante, exploiting the weakness of a boy exposed to his demonic influence in his dreams, is awakened from a thousand-year sleep. The intent of this being, a survivor of an ancient and forgotten civilization, is to wipe out the whole human race.
But it's not that simple: the motivations of the demon aren't so wicked as one might think, and they will combine with the life of the boy, which hangs between nightmares and craziness. In the meanwhile, the Satanists fight against the hierarchy of the church to obtain a justice which is, as it's easy to guess, that of the demon Mao.

This series didn't have an ending until its remake in 2002. Nagai took many ideas from Mao Dante into Devilman.

Mao, who likes plants and does things at his own pace, has been enrolled into the prestigious Eiou Academy (Ougaku for short)! He becomes friends with his mixed roommate, Louis, and might become entangled in a romance with a mysterious beauty.

The young girl Moli who was about to enter high school, was struck by lightning while running late and was sent to Continent of Mingzu. What is this, so it’s a Q version of a world?! What about the promised beautiful youth! Oh well, at least everyone is half beast~ I’ll reluctantly join in for the time being! The status of a magician or some other heavy responsibilities like that, I don’t want it. I just want to foolishly spend my sweet time being. Selfish!