Mutsumi Akira and Nana Negaro are Dragon Society Cardbearers investigating a string of murders in a neighborhood and during the battle they meet Guran Douma a.k.a the Mad Hand's White Dragon, Pylon, in his search for the "Rainbow Death Stanza" group.

After being the only survivor in a plane crash and losing his parents Ryouga, a young boy, is troubled by nightmares and taunted by other kids at his school. Fed up, he agrees to transfer to another school intrigued by a mysterious offer and the hope they may know why or how he was able to survive the crash. Arriving at the new school, he learns he must play a little card game with three others before being accepted... one card each, one vicious monster each, gruesome deaths for all save one.

The mafia boss of the Iwashi family is a high school girl named Konomi Minoko. But don’t let her appearance fool you; she has done and seen things normal citizens can’t even imagine. Under her control are two assassins who have gained legendary status for their deadliness and ability to get any job done. Ishikawa Rushia, codenamed Baret, uses a modified handgun that uses a custom made hollow point bullet that explodes the target from the inside. Shirato Marin, codenamed Francesca, uses a original weapon that is a mix between a throwing axe and battle axe. Both of them are Minoko’s high school classmates and seem like normal teenagers but are two of the most feared killers in the mob world who handle missions often involving other assassins and underground groups.