In this universe, witch power exists as an invisible but invincible power. "Witch Sister" is a tale of two siblings who inherited witches’ blood—the older brother Kyoma, a rookie inspector who could not use any magic and Mikuni, the shut-in little sister who once had gone to witchcraft school. Together they solve grotesque and eerie cases caused by the witches' magic...

For thousands of years, demons have lived in human society. Hundreds of years ago, Japan created a secret society of swordsmen who will battle these demons. Our main characters battle demons and save countless lives as well as learn a little bit about each other.