The young man Cole dreams of one day joining the holy clergy and departs on a journey from the bathhouse “The Spice and Wolf Inn,” owned by his savior, Lawrence. The Winfiel Kingdom's prince has invited him to help correct the sins of the church. But as his travels begin, Cole discovers in his luggage a young girl with a wolf's ears and tail named Myuri who stowed away for the ride!

In the past, Cole had accompanied the Wise Wolf Holo and the traveling merchant Lawrence on their own wanderings, eventually growing up alongside their daughter, Myuri as siblings. But as Cole prepared to set off, Myuri opposed his departure, and so she secretly ran away from home to join him!

This is the story of Wolf and Parchment, and the pair's travels that will someday change the world!

From Yen Press:
With his carthorse as his only companion, the young merchant Kraft Lawrence slowly wends his way through dusty back roads in search of profitable trade. But this monotony screeches to a halt when, one night, he encounters a harvest goddess in the guise of a beautiful young girl…with wolf ears and a tail! Longing for the northern lands of her birth, Holo the Wisewolf joins Lawrence as he follows the ebb and flow of trade through the countryside. And when the two come across a compelling but suspicious opportunity for profit, will Lawrence with his mercantile chops and Holo with her ancient instincts be able to separate the truth from the lies — and make some coin while they’re at it?

Takato Kei is just an ordinary college student, training for an ordinary life, when he falls onto a strange but appealing part time job. He's been hired to tutor a teenage girl at home for 10,000 yen per hour! The girl in question, Fujioka Yukari, is not a high school student, but a highly successful day trader who has already amassed 170 billion yen! Despite her money and her beautiful apartment, Kei can't help feeling that there's a certain loneliness about the cute teenage girl. She even seems embarrassed of her career, as if her obsession with the stock market and the vast amount of time she spends moving stocks makes her an otaku. Kei may be just the person she needs to help her break out of her isolated lifestyle and acquire the one thing money can't buy - happiness.

(*Although the main story as been fully scanlated, the Extras from the tankobon are still unscanlated.)

It is a world where order is maintained by three great factions, the Church which bears the greatest authority, the Order of Clausius possessing influence on par with the Church, immense assets and military might, and lastly the Guild of Commerce, an association of merchants and artisans alike.
The alchemist Kusler who was captured and imprisoned because he committed the offense of trying to burn a saint's bones, sold his skills and talents to the Order of Clausius. Together with an old friend, Welland, they were then dispatched towards the town of Grubetti which was close to the front lines.
And then at a workshop in Grubetti which boasted advanced equipment due to being near the front lines, Kusler met the devout nun Urle Fenesis who had introduced herself as a "watchdog."