In Yoshiwara (present-day Tokyo during the Edo Period), the laws against prostitution were abolished and brothels were restored in the red light district. We meet Kichou and his "princess" who are the top courtesans of the Men's Brothel Quarters at Hanafurirou...

Me de Shireru series:

V.1 - Toku Hen
V.2 - Keisei Hen
V.3 - Hanazono Hen

Asai Fubuki hates interacting with people. To her, everyone looks faceless and monotonous.
So why is she able to see the face of one particular person?

From Intercross:

1) Oikaketemo Chikazuitemo
When she was small, Uiko exchanged a promise with childish Mako that when they are high school students, if they become a couple, they will kiss. All this time, she hasn't been able to forget that promise. But now that they've become high school students, Mako is a popular guy in her class, and Uiko is a plain girl without any redeeming points. No matter what she does, she can't be honest to Mako, who already belonged to a different world before anyone knows, but...?

2) Santa Claus wo Dakishimete

3) 1000% Aisuru Kimochi

4) Suki Sugi Chatte Gomen ne
Chikage has been dating Manato for 3 months, they've held hands, and kissed too and now finally Manato has asked Chikage over. Even though Chikage has mentally perpared herself, can she really take that important next step?

5) Aishi Kimi wo Dakishimete

Tsubasa Shiina is a fourth grader who just moved to Hokkaido with her father. Shy Tsubasa has a hard time making new friends at school. Her father is concerned, but he's just too busy with his new job. He even shows up late on Parents' Day. One night, Tsubasa sees a strange-looking object falling from the sky. Is it a spaceship!? It falls right into the woods by her house. It turns out to be a wounded alien in a damaged spaceship. All of a sudden, a monster starts coming at Tsubasa! Tsubasa suddenly transforms into "Figure." Confused and afraid, she somehow manages to defeat the monster with her new unbelievable power. After the fight, Tsubasa sees a girl who looks just like her--the girl's name is Hikaru!

An informational manga that involves living in Akihabara and reporting on all its interesting spots from personal experience.

The story is set in a dystopian alternative present where any kind of substance able to alter the state of mind is legalized and authorized for consumption at home or in designated places called Pomp Bars.
These products, once considered very dangerous, are now freely advertised on TV. The bartender chooses the ones more suited to his customers and serves them with special cocktails.
When the Pompies movement obtained the liberalization of the drugs it seemed a historically meaningful change destined to improve the world - a dream realized in a manner that radically affected humanity's way of life.
But in a world where all feelings are artificial and where everyone is a potential drug addict, nothing has really changed for the better. Only a select few drugs are considered dangerous and put under strict control by hygiene offices, which is given full authority to handle matters related to the severely addicted.
Kabu, a small-time peddler and heavy addict. Used to any kind of hallucinogenic trip, he is able to feel the happiness through the ecstasy of the drug, while on the same time hypocritically hating who gave birtn to that society which has forced him to the live this way.
After an overdose caused by mixing two incompatible drugs, he spends his days looking for stimulants until the encounter with an enigmatic man who offers him a new kind of illegal substance. Ultraheaven.
From that moment on his incredible journey begins - where dream and reality are fused in an undivided world - causing him both hysterical joy and unbearable pain.

From Fantasy Shrine:

Blessed with looks and brains, Tsubasa is cool with everyone except the devil-may-care Tokimaru, whom he refuses to open his heart to, in fear of Tokimaru's safety. As fate would have it, they are both dragged into another dimension when an unknown entity attacks them and tries to snatch the "secret" from Tsubasa. For 2 months, these two venture in the wonderland where pirates and wizards roam! What in the world is the "secret"? And who is the blond pirate, Silver, who seems to be helping them?

Note: The publisher, Biblos, was shut down and this series was cancelled as a result.

Recently an exceptionally skilled female detective has appeared, and the identity of this highly talked about figure is actually high school student Seika. The case she has taken on this time involves the search for a client's missing younger sister... but now even the younger sister's fiancé has gone missing...!?

By a shiny day, the older brother of Shunta, a potter, made a beautiful clay doll looking like a girl and called Nene.
She was so cute that Shunta couldn't help wishing that she was a real girl... and then a miracle happened, the next day, Nene was alive, moving and creating living dolls by kissing clay dolls.
So begins the life of Nene the doll, a shiny life soon disturbed by a strange inventor, creator of a male android.

From Impossibility:
One day, two high school students find that they are able to communicate to some of the dolls in the art room. The dolls tell them that the only reason they are able to hear them is because they are still "naive"/"childish". However, some events cause the girls to grow up and start losing the ability to communicate with the supernatural...

From Lovers Dream:

It's about a girl who falls in love with her little brother. She thinks it's bad, but the two of them learn that they are not related by blood.

Mei and Takeru are twins who have a very close, if slightly flirty, relationship, and are quite popular within the school. Their relationship is both a source of amusement and dismay to both the male and female school population, especially with Mei, whose massive brother complex keeps her oblivious to serious confessions from other males. Their relationship becomes even more complicated, however, when the two of them learn that they are not related by blood.

Otokogi power!

Kodai lost his younger sister in "Noah's Flood", a catastrophic event that submerged Tokyo not too long ago. He confines himself to what's left of his old life, refusing to move on. One day, a mysterious girl who calls herself "Kururi" jumps out from the endless sea, claiming that Kodai's "home" actually belongs to her. After a brief chase from some mafia-type group, Kururi forces herself into Kodai's life as his new roommate. Because of this, Kodai is forced to start moving on from his tragic loss and both of them have to learn to adjust to the new way of life that "Noah's Day" forced everybody to live.

What do you get when you mix together a wacky wizard, a girl who loves fairy tales, and a pair of enchanted footwear? Anything can happen to those who wear these magical boots which have "unlimited power", and things get crazy (crazily funny) when love goes awry in this cute, two-chapter story by Wujian and Wulin.

From Tokyopop:

An uncatchable thief is plaguing the city. No one knows her true identity and the police are unable to stop her. She is only known as Saint Tail. At St. Paulia Junior High, a young student named Asuka Jr. makes it his mission to find, stop, and apprehend the elusive Saint Tail. Little does he know that the nocturnal thief is really his friend, Meimi. Aided by a novice nun, Meimi steals to help the needy. Don't miss any of Saint Tail's magical exploits in the tale of this modern day Robin Hood.

Moving into a boarding school for the first time Sakurashima Minato accidentally goes to the wrong building and encounters a strange man in a white coat, who calls him a martian and offers to help him take over the world. Minato's not very bright so he could be in alot of trouble here...

Little Busters! revolves around Riki Naoe, a young male high school student. When Riki was a child, his parents died, leaving him hopeless and depressed. What saved him was a group of his friends who referred to themselves as the Little Busters; they took Riki out and played together with him during his time of need. He really enjoyed playing with them, and his grief gradually faded away. When the story begins, they are in their second year of the high school they attend. They still hang out together, and enjoy their school life.

Toki is a former Hokuto practitioner, and his incredible strength coped with his knowledge of the assassin art would be enough to call him devil.... But Toki's kindness and desire to help people prevent them from calling him devil, they instead can only whisper words akin to that of 'savior'.

From Del Rey:
Yamato is ready for a fresh start. So when his aunt invites him to stay rent-free in her big-city boarding house in hustling, bustling Tokyo, Yamato jumps at the chance. There's just one teensy-weensy catch: It's an all-girl housing complex and spa! Things get even more nerve-racking when Yamato meets his neighbor Suzuka, a beautiful track-and-field star. She's not just the cutest girl Yamato's ever met, she's also the coolest, the smartest, and the most intimidating. Can an ordinary guy like Yamato ever hope to win over a girl like Suzuka?

Azusa, known as the 'jewel girl', is one of the few remaining, living members of her family, that was gifted with a unique ability - according to her own emotions, she can turn flowers and plants into precious jewels. Held captive and working for one of the country's Lords for 10 years, the only thing she was looking forward to was catching a glimpse of the Lord's second son who was very kind to her. But now that the boy has suddenly disappeared, her ability has started to diminish. Azusa runs away to find him, only to stumble upon Monji, a young thief who makes an interesting deal with her.

(Source: Batoto)