Hayate Ayasaki, 16, the world's unluckiest boy. Working hard as a child for food and school fees, his unemployed and indebted parents sold him to the yakuza for his internal organs. After temporarily escaping the criminals and contemplating the benefits of a life of crime, he was saved by a wealthy young girl; who now employs him as a live-in butler.

Yuuka Yoshimi is a young woman working in a Eroge studio who is learning how to make good ecchi CG.

From TokyoPop (based on volume 1):

The World at the Brink of Self-Annihilation

The nuclear age has brought with it the arms race, which has led to the advent of weapons powerful enough to destroy the world itself several times over. Unwilling to take the plunge into Armageddon, the world powers, in league with a group known only as the Black Ghost, have developed super soldiers known as the Cyborgs, designed to fight the wars of the world in space. Unfortunately, the Black Ghost didn't ask the Cyborgs how they felt about their role in the new world order.

This classic work from manga legend Shotaro Ishinomori (Masked Rider) not only told a thrilling tale set against a backdrop of Cold War tensions, but it also helped define the genre of super team stories such as Battle of the Planets, Voltron, and The Power Rangers.

Two sets of friends come together to form a tight-knit group. Things become interesting when Nao spots Aoi's feelings for Chihiro.

All her life, Chihaya's dream was to see her model sister become Japan's best... That is, until a quiet, unassuming transfer student named Arata tells her otherwise. A dream, he explains to her, is something she needs to work at herself.
Arata plays a competitive version of a traditional Japanese card game, known as Hyakunin Isshu, in a way Chihaya has never seen before. After taking Arata's place in a game, Chihaya discovers she has a passion for it. Now Chihaya wants to become number one in the world, the Queen of Karuta.

Note: Won the 2nd Manga Taisho Award and the 35th annual Kodansha Manga Award for Best Shoujo.
Was nominated for the 20th Tezuka Osamu Cultural Prize in 2016.

Having returned to college after a year long break, Hong Sul, a hard-working over-achiever, inadvertently got on the wrong side of a suspiciously perfect senior named Yoo Jung. From then on, her life took a turn for the worse - and Sul was almost certain it was all Jung's doing. So why is he suddenly acting so friendly a year later?