This is the Ayase route of the Oreimo storyline.

Ponta anxiously awaits the first big event in his high school life that will give him the opportunity to lose his virginity. A trip to the beach with his friends Taro and Jiro, in the company of three girls, Emi, Rumi, and Chisa. Coupling is done by janken and Ponta ends up with Chisa, the girl of his preference. His plans fail miserably though, when it turns out that Chisa is not so willing as he thought she would be. So, at the end of the trip, unlike his friends who tease him about this failure, he still remains a virgin. To his friends' surprise though, Chisa turns around and asks him to keep in touch.
Thus begins the romance between the two. Their friendship evolves into love, and like in any relationship, there are a few hurdles to overcome. For starters, Chisa is still very innocent and has good reasons not to hurry their physical relationship as much as Ponta would want to. Ponta, who has hopelessly fallen for her, decides to endure this and help Chisa uncover her womanhood.

The story of a young boy Kamui growing up to become a ninja. His life of training ends when he realizes that he doesn't want to be a ninja and decides to become a nukenin (outlaw ninja), someone who is not affiliated with an organization and is hunted for leaving the clan...

Space is mainly inhabited by three different groups: the Federation, which is the real government; Various pirate clans, which use special techniques and magic to dominate the frontier; and the outlaws which are just about everywhere in between. There are also various alien races and empires which sort of fall within this category. It is on this frontier where Gene Starwind and his 11-year old partner Jim Hawking, freelance bounty hunters and odd-job takers extraordinaire, live and work. Until they happen to take a job from a mysterious woman named Hilda. In no time flat they're up to their ears in pirates...

Eulji So Moon has aged well and is now a grandfather. He orders his mischievous grandson to go on a joyful trip to Zhongyuan! To save the fallen Namgung family clan and help them spread their wings once more, Eulji Ho’s journey starts now!!

1945, Ueno. The souls of those that lost everything burst at the ruins left by the war.

Kanekichi, a war orphan who lost his family continues to struggle in despair.
But upon meeting a mysterious young man, Kanaida, the boy's heart starts unraveling ...?

When the blue moon rises in the sky, don't get hit by the moonlight, or else...
Should the moonlight touch you, you will become a monster.

Two weeks after an incident on a bus, Jangmin receives a warning from his phone: "Direct moonlight will cause symptoms of skin changes, mental distress, etc. To prevent exposure, citizens are forbidden from nighttime activities."

But at nightfall, hundreds of texts invite him to come outside and look at the moon...
A series of bizarre events is about to begin...

The manga follows a maker of individually crafted shoes after he returns home from a trip to Florence, Italy. One day, a surprise visitor comes to his studio.

In a town with nothing, in the middle of a daily life with seemingly no signs of change, high schooler Reiji Kurose was "just" living. Family, dreams for the future, childhood friends. All of them were binding him down to that city. He thought he would "just" keep on living like that. Until he met her. Is there hope in living? Is there light waiting ahead? It's the start of a boy meets girl series which reflects the "now".

By the author of Hatsukoi Zombie

In a city so over-indulgent and careless, reveling in food and sex and completely unaware of the epidemic of parasites, it's no wonder so many people are infected. Dr. Suzune Arizono isn't exactly a normal doctor. For one, she's actually a veterinarian— but her specialty is parasites, and when those parasites make a habit of nesting inside human genitalia and overriding their senses with lust, her job is bound to get more than a little messy!

As the spunky and beautiful heroine of this sexy sci-fi mystery, Suzune searches for infected victims to stop the parasites from driving their hosts literally crazy with lust. However, despite her desire to help people, her reasons aren't completely selfless. The parasites are Suzune's only link to her missing father, but will following these wet and slimy clues really lead her to his whereabouts, or is this voluptuous vet in over her head?

Gen Suzuki, a young man who grew up in an orphanage, is trying to live an honest life. But when the cruel reality of the 10 million yen debt from her sister hits him, he decides to rob a Dark Casino. What awaits him is the baptism of the underworld!

The story centers on an ordinary high school boy named Keita Amano. His hobby is video games, but apart from that, he has no conspicuous traits, and has never been in love. As Keita continues his gaming life, he suddenly becomes involved with Tendou Karen, the most beautiful girl at school and the president of the school's video game club. She shocks Keita when she asks him to join the video game club.

Watch how their relationship evolves and becomes more complicated, especially when other gamers come into the picture, creating all sorts of misunderstandings and drama.

After Dean, a third rate adventurer, got surrounded by demonic beasts in the demonic labyrinth, he fled to a place where he found the strongest demon who devours power: The demon-fed sword Belzera, born to the Gluttony Empress Belzebuth. After obtaining such unexpected power, he once again aims to become a first-rate adventurer he looked up to, and delves deeper into the labyrinth. However...

When he was a child, his father was said to have died from a car accident. But what actually caused his death was ‘Medical Negligence’. Ever since that, his dream was to become a ‘Perfect Doctor’ that would never deny or mistreat a patient.

However, reality was harsh. His mother was inflicted with an incurable disease, which required a lot of money. He quit his university hospital internship and became a sell-out dermatologist.

While he had stopped in his tracks due to the harshness of reality, a state-of-the-art Artificial Intelligence, ‘A.I. – Ronnie’, came to him. And thus, his journey to become a perfect doctor started once again.

The trials and tribulations of a single father, who one day meets the reincarnation of his deceased wife.

Synopsis from Kadokawa:

Cheats for fluff! The reincarnated Saint doesn't care about dignity!

Kanata is a girl known as the reborn "Saint". With such talent, the profession she chose is... the weakest "monster tamer"!?

Kanata, who finished her previous life alone in a hospital room, only wants to adore and become friends with fluffies all over the world! If there's a dragon aiming for fluffies in the east, it'll be punished with powerful magic, and if there's a foul smell in the west, the entire city will be purified so the fur won't smell!

When I used my cheats for fluffies, I was worshipped as a Saint by the people I accidentally saved!?


Synopsis from Niconico Seiga:

"Finally, finally... I can touch fluffies!"

Kanata is a girl known as the reborn "Saint". With such talent, the profession she chose is... the weakest "monster tamer"!?

That's right, Kanata, who reincarnated from a previous life of loneliness, has chosen to use her cheats to pat all the world's fluffies. All you have to do is adore them to the fullest!!

A fast-paced girl's otherworldly adventure story, comicalized! ☆

Artist's Twitter: https://twitter.com/iida_101
Web Novel (Raw): https://ncode.syosetu.com/n5694fk/

Housen is a painter of erotic art in the Edo period, who stumbles into a murder mystery involving women who have hooked up with one of his patrons. With the help of Tsubaki, a girl he runs into on the street who seems to know more about him than he does and is an artist herself, they start unraveling mysteries involving sex, murder, and occasionally the occult...

A sci-fi where the bar for suspension of disbelief is set very high.

Nakamaru Koutarou, a high schooler and skilled kendo practitioner, has his peaceful life shattered when a mysterious virus with a 94% infection-fatality rate puts Japanese society on the verge of collapse and threatens the whole world. Right when his little brother is infected, he is scouted by an organisation at the forefront of Japan's last ditch-effort against the virus: miniaturise a company of daredevil soldiers to capture the new life form that acts as carriers for the pathogen, so they can be used as a source for a vaccine/antiserum!

No kidding. Enjoy.

“If I were given another chance…” 10 years after the apocalypse began on Earth, while he faced imminent death, Yoohyun was filled with regret. Just then, a bright light descended upon him. When he opened his eyes, he was greeted by an unfamiliar scene… Not only had he reincarnated as a non-human race called “Teller,” but he had also traveled back in time by 10 years! “Now that it has come to this, I’ll live my best life this time!” Unlike his previous life, where he was solely focused on survival, he is now determined to lead a successful life. In this new life he has gained, will Yoohyun truly be able to become the protagonist?

Luna, a princess of the Cosmonaut Kingdom who lost her sister when she was little, only opens her heart up to her best friend. But now that her best friend has gone missing, she runs away in hopes of never losing another loved one again.