The long-eared people has always lived harmoniously in their community. One day, a child of the fearsome round-eared people suddenly appeared in their village. Due to a misunderstanding, the child became infuriated and transformed into an adult with tremendous strength. The usually peaceful village was thrown into chaos due to the child's presence.

From Broccoli:
When Kaya runs into trouble one day, it’s not a knight in shining armor, but her stuffed animals that come to her rescue. It may sound crazy, but Kaya isn’t pretending: she loves her stuffed animals so much, they come to life and turn into people! Plushies come in all different shapes and sizes, and so do their hearts—whereas some are nice, there are others who are not so kind.

From Tokyopop:

Beings who possess animal-like powers walk among humans in this alternate universe. These mysterious mutants, the +Anima, are shunned by society. Four outcasts in particular--Cooro, a boy with crow-like powers; Husky, a fish-boy; Senri, a bear +Anima; and a girl named Nana, who wields the power of the bat--search for others like themselves while trying to gain acceptance in a world cruel to anyone or anything that is different.