Misato Takuma, who has a crush on a classmate, is suddenly kidnapped at the infirmary when he comes to have a second checkup. When he wakes up, he's strapped to a bed and forced to do "something" by a beautiful nurse he doesn't know! It's a mysterious hospital where men are locked in an isolation ward and managed by beautiful women! Where the hell are we? And what is the purpose of these beauties? And then the love game between a woman and a man with their lives on the line begins!

Fujishirou Kousuke is currently an unfriendly and unsociable high school student. However, when he was younger, he made a promise with his childhood friend, Sayaka, that they would get married when they grew up. But one day, Kousuke is kidnapped and taken to a place that strangely resembles a prison. Little does he know though, is that this "prison" is guarded by very voluptuous women... Can Kousuke remain a virgin to fulfill his promise to Sayaka?