Taken from the Holy Scriptures of the Old Church of Selakiel:
"When the Earth begins to perish, the Messiah will descend from the Heaven on wings of light. Clad in darkness, he will be so little yet he will be so immense surely he shall bring salvation to everyone."

"The four saints shall appear to offer him their assistance. One will give the Messiah courage, one will give the Messiah light, one will give him wings, and one will shield him from his enemies."

Note: Chapters are numbered differently starting on volume 7, since it's a beginning of a new arc

The manga is separated into 3 story arcs with close to none relation with each other's characters.
Volume 01-13: Video Girl Ai
Volume 14-15a: Video Girl Len
Volume 15b: Video Girl - Complete Story (about Video Girl Haruno)

Video Girl Ai [From Viz]:

High-school student Yota Moteuchi is so unpopular that his classmates have given him the nickname "Dateless." So it's no surprise when the love of his life, Moemi, is not interested in Yota but instead is in love with Yota's best friend, Takashi. Yota turns to a video rental shop for comfort, but little did he suspect that the shop was magical and that the cute girl on his rented tape would pop out of the television and try to fix his ruined love life!

Randou Masashi, a self-centered, brash karate star, was the victim of a horrific bus accident that left him comatose, his face terribly disfigured by extensive burns.

Genius plastic surgeon Dr. Manabe saved Randou's life and went to work on his face, gradually reconstructing it based on a photograph found in the wreckage of the bus. But in a cruel twist of fate, the photo that the doctor used as his reference was not a picture of Randou, but of Rina Kurimi, the girl whom Randou has a crush on!

Ten-year-old prodigy Negi Springfield, has just graduated from magic academy, and in order to become a master mage he is sent to Japan to teach English at an all-girls middle school. But Negi has a bigger dream than just becoming a master mage. He wants to find his missing father, "The Thousand Master", the strongest mage that has ever lived. And he soon finds that searching for his father wont be as easy as he first hoped. In fact, it pushes him and his students into life-or-death battles that decides the fate of millions.

Sakura is the princess of Clow - and possessor of a mysterious, misunderstood power that promises to change the world. Syaoran is her childhood friend and leader of the archaeological dig that took his father's life. They reside in an alternate reality where whatever you least expect can happen - and does. When Sakura ventures to the dig site to declare her love for Syaoran, a puzzling symbol is uncovered - which triggers a remarkable quest. Now Syaoran embarks upon a desperate journey through other worlds - all in the name of saving Sakura.

Not particularly good at sports, not very popular, and not very good at school, Naoki's middle school years are filled with video games and erotic books. But one day, a cute girl called Iroha appears, claiming to be his daughter from 20 years in the future. Apparently, in the future magic has been discovered, and she has come back in time by magic to protect her beloved papa from a dark future.

A Byouma is a medical weapon created by ancient sorcerers to kill the infected or those around the infected and make it look like an illness. Even centuries after the sorcerers have died, these weapons still wander the world, infecting and killing people. Narutaki Soutaro and Izumo Momo are Shadow Doctors, trained to combat these Byouma through unorthodox means. Using magically created anti-Byouma medical equipment, they perform “operations” on the medical weapons to separate them from their hosts and destroy them. Will their special weapons and brilliant teamwork be enough to get rid of all the Byouma in the world?

From Pink Everlasting Dream Scanlations:

Sakura Aki is a penniless high schooler who likes to cook and does other "unmanly" things. His grandfather and father are disciplinary on gender roles and beat up Aki everytime he does a thing that women would usually do, like cleaning. When his father leaves him absolutely broke, and with his grandfather realizing Aki's "unmanly" flaws, he sends him to live at one of the dorms at an all girls' school that he runs, a school where distinguished young ladies of the country attend, the Hanayashiki - Flower Estate-, to teach him a lesson.

He meets Kitahiro Renge, a girl with un-ladylike manners and a meat loving obsession. An encounter that's going to save Aki Sakura or just another problem in sight?!

In the near future, the National Police Agency establishes an elite covert paramilitary division called Minkei or Private Police in English to tackle violent criminals and gangs. Among its operatives include average school student Kou Shirashi and school idol Mikuru Nazume.

Aoshima Hitoshi is a second-year student in high school, who wishes he had a girlfriend. One day he wakes up for an unknown reason 10 years in the future, and he is married to the prettiest girl in school, Wagatsuma Ai! How has their relationship grown from mere acquaintances to husband and wife!?

The hero who's called a demon by his enemies, Yasuzaki-man, destroys the monsters that feed on people! But even heroes have worries…!?

Taken from Anime News Network:

Changing schools is something Yuuchi is accustomed to, due to his parent's profession, and with their recent venture to Africa, he is returning to his aunt's home after 7 years. The time that has passed since his last visit has faded his memories of the people he knew, and the ties that bonded them to him, including his cousin Nayuki. Slowly those people, coincidently all being girls, find their way back to him. However, time has passed and things have happened in their own lives that sets the tone for the series. Secrets that are coming to surface, and memories that are returning to not only Yuuichi, but to those surrounding him. A very heartwarming tale that touches upon a spectrum of emotions, mystery, and the supernatural.

The story is focusing on Yutsuki Onomiya as heroine.

From MangaHelpers:

Sagara Masamune is a manga author who isn't very successful, and it's looking like it's time to end his battle manga. To go for an unexpected ending, he plans to kill off the main heroine, Nina, in a dramatic way. As he works on his manga, he is mysteriously sucked into the pages. Now he's trapped in the world of his own creation, with his protagonists, exorcists Haru and Nina. He doesn't really get what's happening, but he thinks concluding the manga, which involves orchestrating Nina's death, might get him back home. [tethysdust]

She's a second-year high school student with a single all-consuming question: Will the boy she likes ever really notice her? He's the school's most notorious juvenile delinquent and he's suddenly come to a shocking realization: He's got a huge crush, and now he must tell her how he feels.

NOTE: Chapter 232 does not exist, there's no chapters missing.

At the dawn of the 17th century, at the end of the era of civil wars, in a world of chaos, the epic Battle of Sekigahara was joined.
One man emerged from the largest battle ever fought on Japanese soil; a terrible warrior of unspeakable power, he was nicknamed 'the unconquerable.'
Kyoshiro is a peaceful medicine peddler who harbors the soul of an assassin. He accompanies a young bounty hunter across Japan in search of a murderer and on a quest to discover the terrible secret of his own identity.

From Dark Horse:
Dark Horse proudly presents another of the crown jewels of international graphic fiction—Astro Boy! Created by the late Osamu Tezuka, a revered animator and cartoonist—who created over 150,000 pages of comics in his career!—and considered the Walt Disney of Japan, his Astro Boy was the first manga series to be adapted to animation and became a worldwide phenomenon, making Astro Boy the Mickey Mouse of anime—a jet-powered, super-strong, evil-robot-bashing, alien-invasion-smashing Mickey Mouse, that is!
Exciting, whimsical, and touching, Astro Boy hearkens back to the classic era of comics and animation, featuring stories that readers young and old will enjoy.

Ichiru Kanzaki is given an offer he can't refuse: to clear his entire debt, he has to enroll in the high school where his father works to track down his father's illegitimate daughter, his own younger half-sister, whom he has never met. But which girl is she?

Futagami Sousuke, 14 years old, is a normal student, wishing to live a normal life. But everything changes the day he sees a doppelganger of himself in his house.
Since then, the girl he has a crush on, Amane, will introduce him to another side of his world he had no idea about, and it won't be anymore the dear peaceful days for Futagami.

Tamano Kako and Marunouchi Gaku were the best of friends, but Gaku had to leave with his father to travel the world. However, Gaku promised that if Kako waited, he would come back in 10 years and they would go out. However, right after Gaku left the law of Takkoku was created: If you confess your love to someone, you must beat them at a game of ping pong; if you touch each other before the game, that person will be punished. If you win, regardless of the other person's feelings, you automatically go out. However, Kako is called the best ping pong player in Japan and Gaku has never played ping pong before AND he wants to be the one that confesses. How will these two people's love flourish under these conditions? Will Gaku ever be able beat Kako at ping pong?