Humanity's dream... Crystal humanoid technology. They have 'illnesses' just like humans but the treatments options are quite different.

The troubled AI's band together, and the new doctor at the facility, Sudou, bears witness.

From MangaHelpers:
This is another story in the Full Metal Panic universe, set ten years after the events with Sousuke and Kaname. Ichinose Tatsuya is a pretty normal high school boy, who lives with his father and little sister Yukari. He has a tendency to fall in love with foreign women, which has never turned out well for him. One day, while up in the mountains driving a Power Slave to help out with his father's company, he runs into yet another beautiful foreign woman, called Adelina. He lends her a hand and is surprised to see that she has a military Arm Slave, called "Shadow," with her. What is this mysterious and highly armed woman doing up in the mountains? Tatsuya's life is about to get a lot more exciting.

In the American Area 51, there is a society where many varied supernatural creatures--kappa, vampires, aliens, gods and goddesses of various mythologies, mythological figures (like King Arthur), and more-- make their home. In addition to the non-humans, there's also a population of humans, people who can't live in the ordinary world for one reason or another. One of these people is Magoi Tokuko, commonly known as Makkoi, a tough woman who works cases with the help of her kappa associate, her deep knowledge of the area, and her pistol. In her office, which she's built in an unfinished subway station, she takes on all kinds of jobs (recovery of stolen goods, infiltration, etc.) from the many humans and non-humans who come to pay for her help.

A 2 volume anthology series featuring A Certain Magical Index and A Certain Scientific Railgun characters.

In December, Miyuki receives an invitation for the Yotsuba's new year's family gathering. However, unlike previous years, they specially added "Everyone must attend" on the invitation. Miyuki understands that "the time has come" — it is time to decide the next head for the Yotsuba Clan.
— If she is elected, her brother will be free.
— If she becomes the next head, she will be forced to marry someone else.
Miyuki's heart is a mess.
The truth of the Brother and Sister relationship is finally unveiled!? Yotsuba Keishou-hen begins!

Adaptation of the original novel's volume 16.

Takagi and Kanemura are two normal high school students in a near-future Japan where many things we'd find unusual are taken in stride.

Technology has evolved to the point where items like face-blurring necklaces, sleep-control devices, and Willy Wonka-ish, meal-flavored gum are common fads. New services also dot the landscape, such as businesses that can help you reclaim memories and places that can upload dead people to the internet to continue living their lives in virtual reality. The two girls treat encounters with androids, strange monsters, and aliens as somewhat normal occurrences.

Dainana Joshikai Houkou is a fantastical slice of futuristic life that proves that, while society can change, people tend to stay the same.

Honjou Kaede was invited by her friend, Shiromine Risa to play a VRMMO.
I don’t hate games, but painful things are a little……no, I hate it very, very much.
Eh!…the pain would be reduced if I placed stats on defense power?
Then, the only place where I can place it, is there right? Right?
Solidly fortify everything into defense, now here I come!

Strider Hiryu was the youngest Strider to ever reach the rank of "Super-A" grade. He was the greatest Strider the organization has ever produced, but he eventually grew disenchanted with them and retired. An uncollected prologue tells how Hiryu had been forced to kill his sister, Maria, who had inexplicably gone insane. He left the Striders for Mongolia, where he lived in seclusion for some years.

The collected manga opens with a Strider assignment gone horribly awry. Two Striders, Kain and Sheena, had been assigned to Kazakh, but were ambushed by a paramilitary organization. Kain and Sheena defended the city valiantly, but were eventually overcome by the simplest of ruses: an armed child. Sheena managed to escape, but Kain was captured by a military officer bearing the Strider tattoo...

Takemichi is a 26-year-old unemployed virgin who learns that the girl he dated in middle school, the only girl he ever dated, has died. Then, after an accident he finds himself in a time leap back to his middle school years. He vows to change the future and save the girl, and to do that he aims to rise to the top of the Kantou region's most brutal delinquent gang. Winner of the 44th Kodansha Manga Awards for best shounen in 2020.

The manga won the 44th Kodansha Manga Award for the shōnen category in 2020.

The future-fantasy world of Remnant is filled with ravenous monsters, treacherous terrain, and more villains than you can shake a sniper-scythe at. Fortunately, Beacon Academy is training Huntsman and Huntresses to battle the evils of the world, and Ruby, Weiss, Blake, and Yang are ready for their first day of class.

Note: This manga is based on the independent American 3D-CGI animated series by Rooster Teeth (created by Monty Oum). The manga itself is a prequel to the original animated series, and delves into the circumstances surrounding the four main characters.

A spin-off of the various works of Kamachi Kazuma. One day, Kamijou Touma (A Certain Magical Index) faced yet another misfortune. His toilet was broken and spraying water everywhere. As he was lamenting his misfortune, suddenly he appeared in a strange place along with Index and Misaka. Soon enough, more strange people begin appearing...

Includes:

A Certain Magical Index
Heavy Object
The Zashiki Warashi of Intellectual Village
The Circumstances Leading to Waltraute's Marriage
A Simple Survey / A Simple Monitoring
Killer Princess and Deep End

The mafia boss of the Iwashi family is a high school girl named Konomi Minoko. But don’t let her appearance fool you; she has done and seen things normal citizens can’t even imagine. Under her control are two assassins who have gained legendary status for their deadliness and ability to get any job done. Ishikawa Rushia, codenamed Baret, uses a modified handgun that uses a custom made hollow point bullet that explodes the target from the inside. Shirato Marin, codenamed Francesca, uses a original weapon that is a mix between a throwing axe and battle axe. Both of them are Minoko’s high school classmates and seem like normal teenagers but are two of the most feared killers in the mob world who handle missions often involving other assassins and underground groups.

In a world driven by fictionalized friendship, courtesy of the program named "Real Account", the table suddenly turns, and the cybernetic world turns real! How will they survive?

This is part 2 of Real Account

The near future, in a quiet seaside town. Yoshioka, who had recently lost his wife, just wants to spend the rest of his days in peace. However, Yoshioka's children, worried about their father's health, sent a housekeeping robot to help him. Yoshioka's quiet life is now changing.

Hitoshi Kobe is a terrible student and an even worse athlete ... though he does have an incredible talent for creating Artificial Intelligence programs. Thirty is his best artificial intelligence program yet -- and, more important, the only girl who will talk to him. Hitoshi's life is forever changed when a freak accident brings Thirty to life ...

In the near future, large mechs called Labors are made to assist in various reconstruction projects in major countries around the world that are being threatened by global warming. In Japan, the government has enacted Project Babylon in order to conduct land reclamation. Labors are also being pressed into police and military service, aside from civilian use.
However, terrorists are now attempting to use Labors to make themselves heard, as well as common criminals, thugs and guerrillas. The National Police Agency established the Special Vehicles Division, an all-Labor task force to combat the potential use of Labors for criminal/terrorist activities.

Note: Won the 36th Shogakukan Manga Award for Shounen manga in 1991.

From Viz:

What do you do when a team of evil superpowered wrestlers from another planet threatens the health and safety of the Earth? Organize a team of GOOD superpowered wrestlers, of course! Kid Muscle, the son of legendary wrestler King Muscle, rockets to Earth and finds an evil wrestling gang called the DMP tearing the place apart. The punks on the DMP are the weirdest, nastiest, most outlandishly powerful musclebound freaks the galaxy has ever known. Kid Muscle's only hope: form a team that's even wilder. Lazy and cowardly, the Kid sure doesn't look like the universe's last great hope, but when something upsets him -like, say, EVIL - he busts out in muscles just like his old man! The only possible result is earthshaking, bodyslamming, ultimate-powered action that sends our entire planet sailing over the top rope!

An introverted Otaku was summoned to a Fantasy world, and successfully defeated the Demon King there. Just before the ritual to send him back to Japan was complete, the country's Princess dashed into the middle of the spell to be with him.

When they both opened their eyes, they realized they were transported to a Sci-Fi themed world than neither of them recognized. Working together, they must now survive in an unknown world and find some way to get home.

A prequel to Chaos;Child that details the life of Kunosato Mio before she got caught up in the events of the Return of the New Generation Madness. It starts from her childhood, and eventually leads to the point that she comes under Makise Kurisu's tutelage.

Chuuta Kokonose is an orphan who lives with his aunt. For as long as he can remember he's had a voice in his head, but other than that he's been a normal boy—right until the day when a strange thing follows him home and teleports him to a place filled with even more fantastic creatures. It's a police station in space.

Surprisingly, Rein Brickke, the Chief of the Solar System Department, tells him that their computer chose him as a potential candidate for the solar-system's police force. However, Misuzu Sonokata, a girl from Chuuta's school with an angelic face and ill temper who turns out to be one of Rein Brickke's subordinates, doesn't think Chuuta is suitable for such a job.

Although Chuuta was shocked at first, he decides to take the aptitude test after being urged by the voice in his head. Most importantly, he wants to prove Misuzu wrong.